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22.
Someone who suffers from the ever popular "Syndrome of a Down". Usually sports a hideously deformed face and torso, crooked almond eyes and drools constantly. Known for ruining innocent, unsuspecting couples' lives with thier selfishness, they are generally an embarrassment to their families. They generally meander around causing unnecessary noise and offending people with their mere existence in cases where "too-nice-for-their-own-good" families have decided not to abort them or throw them to the wolves shortly after birth.
"That dude's a downer - notice the almond shaped eyes, hunched back and pulsating tongue, complete with an incessant flow of drool. Where's the shotgun?"
Jes O'Briar tarafından 10 Mart 2008, Pazartesi
 
23.
What extreme System of a Down fans call themselves. Most likely because they are the most kick ass band out there.
Slipknot fans are maggots, System fans are downers.

Tom: Dude I love SOAD.

Jim: You're such a downer.
beanerwithaweiner tarafından 29 Haziran 2006, Perşembe
 
24.
drugs that are depressants. Drugs like weed.
druggie:"Do you have any uppers"
dealer:"No man only downers."
druggie:*"well when can I see mary jane? I wanna take her on a cheap date."
Last sentence is code for, do you have any weed for cheap.?
Insane tarafından 7 Şubat 2004, Cumartesi
 
25.
Often used in central London and suburban areas for describing not only the side effects of certain drugs, but also an emotional state. Downers, a most versatile word, can be used for a multitude of purposes.
That guy is on the downers.
Your so downers.
this is downers, whens the next train?
your mum is so downers.
Your sexual preferences are on the D (shortened illiteration).
Jambowana tarafından 31 Mayıs 2005, Salı
 
26.
All the dumb ass holes on here who vote "Thumbs Down" on some of the most awesome and understandable stuff on this site.
Damn!Who could posibly vote "Thumbs Down" on THIS!Damn thoughs Downers!
Darka tarafından 31 Ekim 2007, Çarşamba
 
27.
Those annoying shits who put a thumbs down on every definition of a word.
That guy is such a dick. I took my definition out of the dictionary, he still gives it a thumbs down. I'm like WTF! He's one of those downers
Josh King tarafından 3 Kasım 2007, Cumartesi